C2395-13D
CD42b (CD42b Antigen, CD42b alpha, Antigen CD42b alpha, BSS, Glycocalicin, Glycoprotein Ib (Platelet) alpha Polypeptide, Glycoprotein Ib alpha, GP-Ib alpha, GPIb-alpha, GPIbA, GP1BA, MGC34595, Platelet Glycoprotein Ib alpha Chain, Platelet Glycoprotein Ib alpha Polypeptide, Platelet Membrane Glycoprotein 1b alpha Subunit) (FITC)
Size
£601.00
- SKU:
- C2395-13D
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography from tissue culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Clone:
- 3H1309 (AK2)
- Format:
- Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
- Extra Details:
- The GPIb/IX complex (CD42a-d) serves as a receptor for von Willebrand Factor (vWF) and thrombin, and mediates adhesion of platelets to subendothelium of damaged vascular walls. The absence of the CD42 complex leads to the Bernard-Soulier Symdrome (BSS). Antibody inhibits the ristocetin-dependent binding of vWF to platelets, ristocetin-induced platelet agglutination, and partially inhibits collagen-induced aggregation. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: neat, 1:10. 10ul labels 100ul whole blood. Optimal dilutions to be determined by the researcher. Excitation Max: 490nm Emission Max: 525nm Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice