CD40 Human, IgG2a Fc Mouse, Fusion Protein (Biotin)

Size

£832.00

SKU:: C2392-02J
Molecular Weight:: 45.6
Purity:: Purified by affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Format:: Supplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3.
Extra Details:: Human CD40 is a member of the tumor necrosis factor (TNF) receptor family and is present on all B cells except plasma cells. CD40 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 plays an important role in B cell activation and the interaction with its ligand CD154 (CD40 Ligand) is essential for isotype switching (1). CD40 muIg fusion protein blocks binding of anti-human CD40 to Raji cells. Molecular Structure: A soluble fusion protein consisting of the extracellular (193aa) domain of human CD40 fused to murine IgG2a Fc (232aa), with a predicted monomeric molecular weight of 45.6kD. Transfectant Cell Line: CHO Human CD40muIg/Biotin Functional Application: CD40-muIg fusion protein blocks binding of anti-human CD40 to Raji human tumor cells. Applications: Suitable for use in ELISA, Flow cytometry. Other applications not tested. Recommended Dilution Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice