C2392-02E

CD40

Size

£544.00

SKU:: C2392-02E
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Murine L cells transfectants expressing human CD40
Clone:: EA-5
Format:: Supplied as a liquid in PBS, pH 7.2, 0.5mg/ml gentamicin sulfate.
Extra Details:: Human CD40 is a member of the tumor necrosis factor (TNF) receptor family and is present on all B cells except plasma cells. CD40 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 plays an important role in B cell activation and the interaction with its ligand (CD40 Ligand) is essential for isotype switching. Functional Application: Binding of cross linked antibody will partially activate B cells. Applications: Suitable for use in ELUSA and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.