C2388-15
CD36 (gpIIIb, gpIV, Thrombospondin Receptor)
Size
£793.00
- SKU:
- C2388-15
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes. Cellular Localization: cell membrane
- Clone:
- 0.N.107 (185-1G2)
- Format:
- Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide, See C2388-15X.
- Extra Details:
- CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Applications: Suitable for use in Function Blocking, Flow Cytometry, Immunofluorescence, and Immunohistochemistry. Not suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Function Blocking: Order C2388-15X. Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Positive Control: Tonsil Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice