C2388-01R1-ML550
CD36 (CD36 Antigen, Fatty Acid Translocase, FAT, Glycoprotein IIIb, gpIIIb, gp3b, gpIV, gp4, Leukocyte Differentiation Antigen CD36, PAS-4 Protein, PAS-IV, PASIV, Platelet Collagen Receptor, Platelet Glycoprotein 4, Platelet Glycoprotein IV, Scarb3, Thrombospondin Receptor) (MaxLight 550)
Size
£837.00
- SKU:
- C2388-01R1-ML550
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- IL-4 treated mouse thioglycollate-elicited peritoneal macrophages.
- Clone:
- 9E27 (MF3)
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
- Extra Details:
- MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. CD36 is an 85kD transmembrane glycoprotein which is primarily expressed on platelets, monocytes/ macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/ aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunofluorescence. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Hybridoma: Y3Ag 1.2.3 myeloma cells with spleen cells from DA rats Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice