C2387-07G
CD35 (CR1) (FITC)
Size
£384.00
- SKU:
- C2387-07G
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Acute monocytic leukemia cells and normal blood monocytes
- Clone:
- 5K281 (E11)
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
- Extra Details:
- The CD35 antigen is composed of four different allotypes having different molecular weights (A (or F)-160kD, B (or S)-190kD, C-220kD, and D-250kD). It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors. Applications: Suitable for use in FLISA, Flow Cytometry, Immunohistochemistry, Western Blot and Immunoprecipitation. Other applications have not been tested. Recommended Dilution: Flow Cytometry: 10ul/10e6 cells Immunohistochemistry: frozen and paraffin sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice