C2387-07F

CD35 (CR1)

Size

£320.00

SKU:: C2387-07F
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Acute monocytic leukemia cells and normal blood monocytes
Clone:: E11
Format:: Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent.
Extra Details:: The CD35 antigen is composed of four different allotypes having different molecular weights (A (or F)-160kD, B (or S)-190kD, C-220kD, and D-250kD). It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.1-5 Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤ 1ug/10e6 cells Immunohistochemistry: frozen sections and paraffin section Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.