C2383-24-ML490
CD31 (PECAM-1, Platelet gpIIa Molecule) (MaxLight 490)
Size
£1,093.00
- SKU:
- C2383-24-ML490
- Purity:
- Purified by Protein A affinity chromatography from tissue culture supernatant.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- PMA–treated U937 cells
- Clone:
- HC1/6
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
- Extra Details:
- MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD31 (PECAM-1, Platelet gpIIa Molecule), a ~130kD integral membrane glycoprotein, is expressed in platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney, skin biopsies from conditions such as sarcoidosis and lepromatous leprosy and bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 mediates cell-cell adhesion. Valuable iin the study of benign and malignanat vaascular tumors. Stainiing for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence. Fusion Partner: P3-x63Ag8.653 myeloma cell line Source: Tissue culture supernatant Applications: Studies of the role of CD31 in leukocyte migration into inflammatory sites and in the process of angiogenesis This antibody will stain frozen tissue sections Suitable for immunoprecipitation studies Suitable for Flow Cytometry either indirectly or directly when labeled with FITC or R-PE Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice