C2381-10S
CD29 (Integrin beta 1) (Low Endotoxin)
Size
£871.00
- SKU:
- C2381-10S
- Purity:
- Purified by Protein G affinity chromatography from cell culture supernatant. Endotoxin: ≤0.1EU/1mg.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Hamster
- Immunogen:
- Purified mouse VLA-4 antigen.
- Clone:
- 6A267 (HM beta 1-1)
- Format:
- Supplied as a liquid in PBS, pH 7.4. No preservatives added.
- Extra Details:
- The murine integrin beta 1 subunit (CD29) is a 110KD cell surface glycoprotein. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation. CD29 is reported to inhibit beta 1 integrin mediated adhesion (1). Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Functional Assays. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:100 10ul labels 10e6 cells in 100ul. Optimal dilution determined by the researcher. Hybridoma: Spleen cells from immunized Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line. Recommended Secondary Reagents: I1903-34E IgG, H&L (HRP) Pab GtxHm I1903-34S IgG, H&L (HRP) Pab GtxHm I1903-04Q: IgG H&L (FITC) Pab Gt x Hm Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice