C2276-10X-BIOTIN
CD25 (Tac antigen, p55, Interleukin 2 Receptor alpha, IL2Ra, T Cell Growth Factor Receptor) (BSA & Azide Free) (Biotin)
Size
£1,013.00
- SKU:
- C2276-10X-BIOTIN
- Purity:
- Purified by Protein G affinity chromatography from ascites.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human interleukin-2 receptor. Cellular Localization: Cell membrane
- Clone:
- 0.N.93 (IL2R.1)
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
- Extra Details:
- CD25, otherwise known as the Tac antigen or p55, is the alpha chain of the Interleukin-2 (IL-2) receptor. The IL-2 receptor is expressed on activated cells including T cells, B cells and monocytes. It is also present on a subset of thymocytes, HTLV-1 transformed T and B cells, EBV transformed B cells, myeloid precursors and oligodendrocytes. IL-2 induces the expression of the CD25 subunit on NK cells. The IL-2 receptor consists of at least three distinct membrane components: the alpha chain (IL-2R-alpa, Tac, CD25), the beta chain (IL-2R-beta, p75, CD122), and the gamma chain (IL-2R-gamma). CD25 is undetectable on resting T cells but is induced upon T-cell activation. Applications: Suitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Positive Control: Tonsil or lymph node Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice