C2269-11A

CD18 (Leukocyte Function Associated Antigen, LFA-1 beta2)

Size

£397.00

SKU:: C2269-11A
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Cell membrane lysates derived from mouse T cell lymphoma BW5147
Clone:: C71/16
Format:: Supplied as a liquid in 100mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
Extra Details:: CD18 represents the common beta2 integrin subunit that associates non-covalently with the alpha beta chains of CD11a/LFA-1a, CD11b/Mac-1, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes, and weakly on granulocytes, CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions, and it regulates the ligand-binding activities of the various CD11/CD18 complexes. The antibody has not been reported to inhibit cell adhesion.1-4 Applications: Suitable for use in ELISA, Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry/Immunocytochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.