C2267-62B

CD16 (FCGR3A, Fc fragment of IgG, low affinity IIIa, receptor CD16a, FCG3, Fc-gamma RIII, Fc-gamma RIIIa, FCGR3, FCGRIII, FcR-10, FCR-10, FcRIII, FCRIII, FcRIIIa, FCRIIIA, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A precursor)

Size

£544.00

SKU:: C2267-62B
Purity:: Purified by Ion Exchange chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Human Fc gamma receptor III
Clone:: 9F605
Format:: Supplied as a liquid in 0.02M Tris-HCl, pH 8.5 0.12M sodium chloride.
Extra Details:: Receptors that recognize the Fc portion of IgG are divided into three groups designated Fcγ RI, RII, and RIII, also known respectively as CD64, CD32 and CD16. In humans, each group of receptors, is encoded by 2-3 closely related genes designated A, B, and C. Fcγ RI binds IgG with high affinity and functions during early immune responses. Fcγ RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.