C2262-56U-FITC
CD11c (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, Leu M5, Leukocyte Surface Antigen p150,95 alpha Subunit, Myeloid Membrane Antigen alpha Subunit, p150,95 Integrin alpha Chain) (Azide Free) (FITC)
Size
£1,119.00
- SKU:
- C2262-56U-FITC
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human CD11c.
- Clone:
- CBR-p150/4G1
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
- Extra Details:
- Human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150, is a ~150kD type I transmembrane protein and member of the integrin alpha chain family expressed by monocytes and macrophages, granulocytes and NK cells. CD11c is a marker fo hairy cell leukemia cells. CD11c combines with CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, and acts as a mediator of leukocyte adherence to the endothelium. CD11c also binds to the ligands CD54 (ICAM1), iC3b ,and fibrinogen. Applications: Suitable for use in Flow Cytometry, Functional Assays, and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 5-10ug/ml; 10ul labels 10e6 cells in 100ul Immunohistochemistry: frozen sections Funtional Assay: Inhibits the binding of CD11c to endothelial cells. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice