C2262-56A

CD11c (Monocyte, Macrophage, Integrin alphaX)

Size

£326.00

SKU:: C2262-56A
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Human rheumatoid synovial fluid cells and fibronectin purified human monocytes.
Clone:: 5K216
Format:: Supplied as a liquid in borate buffered saline, pH 8.0.
Extra Details:: CD11c is a 150kD adhesion glycoprotein that associates with beta2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium (1-6). Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: ≤ 1ug/10e6 cells Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.