C2262-36A

CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (Biotin)

Size

£448.00

SKU:: C2262-36A
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Rheumatoid synovial cells and human monocytes
Clone:: ICRF44
Format:: Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Biotin.
Extra Details:: CD11b is the 165 kDa αM chain which combines with the CD18 β2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2). Applicatons: Suitable for use in Immunoprecipitation, Immunohistochemistry and Flow Cytometry. Other applications have not been tested. Recommended Dilutions: Flow Cytometry: ≤1ug/1x10e6 cells. Optimal dilution determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.