C2262-36

CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)

Size

£320.00

SKU:: C2262-36
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Rheumatoid synovial cells and human monocytes
Clone:: ICRF44
Format:: Supplied as a liquid in BBS, pH 8.2
Extra Details:: CD11b is the 165kD alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b/Mac-1alpha functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).1-8 Applications: Suitable for use in Immunohistochemistry, Flow Cytometry and Blocking Studies. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤ 1ug/10e6 cells Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.