C2262-27C
CD11a (Leukocyte Function Associated Antigen, LFA-1, Integrin aL) (FITC)
Size
£512.00
- SKU:
- C2262-27C
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Clone:
- I21/7
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
- Extra Details:
- Leukocyte Function-associated Antigen-1 (LFA-1) is a member of the integrin family of cell adhesion molecules.1, 2 The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow.2 CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.1, 2 Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilution: Flow Cytometry: 1ug to stain 1x10e6 cells. Immunohistochemistry: Acetone fixed frozen. Optimal dilutions to be determined by the researcher. Recommended Dilution: Flow Cytometry: ≤ 1ug/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice