C2257-05A
CD6 (T-cell differentiation antigen CD6) (Biotin)
Size
£960.00
- SKU:
- C2257-05A
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to Leu18-Gly396 of mouse CD6 expressed in NS0 cell.
- Clone:
- 9i227
- Format:
- Supplied as a lyophilized powder from 0.2um filtered solution in PBS, pH 7.4, 50ug BSA per 1ug as a carrier protein. Reconstitute with sterile 500ul PBS. Labeled with Biotin.
- Extra Details:
- CD6 is a transmembrane member of the group B scavenger receptor cysteine-rich (SRCR) superfamily. It is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. CD6 functions as a costimulatory molecule in T cell activation, and its interaction with ALCAM promotes thymocyte development. Additionally, CD6 mediates the adhesion of T cells to ALCAM-positive neuronal cells. The human and murine proteins share 70% aa identity over their full-lengths. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice