C2252-01P
CD1a (Langerhans Cells)
Size
£1,144.00
- SKU:
- C2252-01P
- Purity:
- Culture supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to the full length external domain of human CD1a.
- Clone:
- MTB1
- Format:
- Supplied as a liquid in 0.09% sodium azide.
- Extra Details:
- At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 is expressed on cortical thymocytes, Langerhans cells, and dendritic cells. It is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes. CD1 proteins have been demonstrated to restrict T-cell response to nonpeptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. This antibody is useful in the characterization of leukemias and lymphomas. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin/paraffin): 1:15 for 30 min at RT. Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min. Optimal dilution determined by the researcher. Positive Control: Thymus Cellular Localization: Cell membrane and cytoplasm Epitope: External domain Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice