CCR8 (Chemokine Receptor 8, CC-CCR-8)

Size

£728.00

SKU:: C2099-72J
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to aa7-33, PNVTMTDYYPDFFTA PCDAEFLLRGSM of mouse CCR8 (C-C chemokine receptor 8).
Format:: Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.09% sodium azide.
Extra Details:: Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The CCR8 receptor in particular mediates CC chemokine I 309 induced monocyte chemoattraction, HIV 1 envelope fusion and virus infection. Applications: Suitable for use in Western Blot, ELISA, Immunohistochemistry. Reported in literature to work in Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin): 1:200 Western Blot: 1:500 ELISA: 1:50,000 Optimal dilutions to be determined by the researcher. Positive Control: Mouse spleen cells. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.