C0116-05B-FITC
Calcium and Integrin Binding Protein 1 (SIP2-28, Calmyrin) (FITC)
Size
£914.00
- SKU:
- C0116-05B-FITC
- Purity:
- Purified by Protein A chromatography
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant Calmyrin protein (full length)
- Clone:
- 1G8C8
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Fluorescein isothiocyanate (FITC).
- Extra Details:
- Calmyrin is identified as a calcium-binding protein with a molecular weight of ~22kD. Calmyrin displays various properties, including myristoylation, membrane-association, and colocalization with presenilin-2 (PS-2). Functionally, like presenilin, calmyrin causes cell death when overexpressed in HeLa cells. Interestingly, calmyrin coexpresses with PS-2, and induces additive effects in apoptosis. These results indicate diverse roles of calmyrin in cell signaling, cell death and Alzheimer disease through the modulation of presenilin function. Applications: Suitable for use in FLISA and Western Blot. Other applications have not been tested. Recommended Dilution: FLISA: 0.1–1ug/ml Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice