CACNA2D1 (Voltage-dependent Calcium Channel Subunit alpha-2/delta-1, Voltage-gated Calcium Channel Subunit alpha-2/delta-1, Voltage-dependent Calcium Channel Subunit alpha-2-1, Voltage-dependent Calcium Channel Subunit delta-1, MHS3, CCHL2A, CACNL2A)

Size

£812.00

SKU:: C0104-70
Application:: WB
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide EPFPS AVTIK SWVDK (C), corresponding to residues 1-15 of alpha2 subunit (residues 27-41 of rabbit alpha2/delta-1 precursor) (UniProt P13806). Epitope Location: Extracellular, N-terminus. Species Sequence Homology: Porcine, human - 100%; mouse, rat - 93% (14/15).
Format:: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Extra Details:: CACNA2D1 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:200; Rat brain membranes. Optimal dilutions to be determined by the researcher. Control Antigen: C0104-70P Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice