c-Fos (Fos)

Size

£735.00

SKU:: C0030-06
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Sheep
Immunogen:: Synthetic peptide (MFSGFNADYEASSSRC; aa 2-17) conjugated to diphtheria toxoid
Format:: Supplied as a lyophilized powder. Reconstitute in 50ul of sterile water. Centrifuge to remove any insoluble material.
Extra Details:: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. Belongs to the bZIP family. Fos subfamily. Applications: Suitable for use in ELISA. Other applications not tested. Subcellular Localization: Nucleus. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.