C0026-10

c-erbB3 (HER 3, ErbB3)

Size

£876.00

SKU:: C0026-10
Application:: WB
Purity:: Purified by Protein A affinity chromatography from ascites.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to rat c-erbB-3 oncoprotein. Cellular Localization: Cytoplasmic and cell membrane
Clone:: 0.N.213 (2F12)
Format:: Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Extra Details:: c-erbB3/HER3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB3 is over expressed in a variety of tumors including breast, stomach pancreas and colon. Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB3 to different extents. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 4ug/ml for 2 hous at RT. Optimal dilutions to be determined by the researcher. Positive Control: T47D cells. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.