B3000-09G

BST2, Recombinant, Human, aa50-161, His-Tag (Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin, CD317)

Size

£576.00

SKU:: B3000-09G
Molecular Weight:: 14.8
Purity:: ~80% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl buffer, pH8, 0.1Msodium chloride, 1mM DTT, 20% glycerol.
Extra Details:: BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Purified by using conventional chromatography. Source: Recombinant corresponding to aa50-161 of human BST2, fused to His-tag at N-terminal, expressed in E.coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS Molecular Weight: ~14.8kD (133aa), confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice