B2702-34A
Brain Natriuretic Peptide, aa1-21 (BNP)
Size
£416.00
- SKU:
- B2702-34A
- Purity:
- Purified by Protein A affinity chromatography from cell culture supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to aa1-21, HPLGSPGSASDLETSGLQEQR of human pro-BNP, conjugated to polylysine
- Clone:
- 21-6-6
- Format:
- Supplied as a lyophilized powder from 200mM Na Citrate-Tris, 500mM sodium chloride, pH 7.5, 0.02% sodium azide. Reconstitute with 10ul or 100ul sterile ddH2O.
- Extra Details:
- Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 1;25 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice