BDKRB1, ID (B1 Bradykinin Receptor, BK-1 Receptor, B1R, BRADYB1)

Size

£696.00

SKU:: B2675-80A
Purity:: Purified by Protein A and peptide affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 213-239 in the central region of human BDKRB1.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Bradykinin, a 9aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Applications: Suitable for use in Indirect Flow Cytometry, ELISA and Western Blot. Other applications have not tested. Recommended Dilutions: Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.