Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)

Size

£353.00

SKU:: B2570-28
Molecular Weight:: 489.64
Purity:: >99% by HPLC
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 7184-60-3
Extra Details:: Borrelidin is an unusual nitrile containing metabolite isolated from Streptomyces. Originally discovered as active against against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery displaying activity against drug-resistant Plasmodia. Purity: >99% by HPLC Solubility: Soluble in ethyl acetate, ethanol, methanol, DMF or DMSO.