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B2555

Bonzo (CT)

Size

£655.00

SKU:
B2555
Application:
WB
Purity:
Purified IgG
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Peptide corresponding to amino acids 319 to 338 of human origin (1,2). The sequence of this peptide is identical to those of macaque and African green monkey.
Format:
Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4). Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes. This polyclonal antibody can be used for detection of Bonzo expression by Western blot at 1:1000 dilution. Whole cell lysate from SW1353 cells can be used as positive control. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Positive Control: Whole cell lysate from SW1353 cells Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice