B2553-33A

Bmp7, NT (Bone Morphogenetic Protein 7, BMP-7, Osteogenic Protein 1, OP-1, Eptotermin alfa, OP1)

Size

£696.00

SKU:: B2553-33A
Purity:: Purified by ammonium sulfate precipitation
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the N-terminal region of human Bmp7 (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:200 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.