BIRC3 (IAP2, cellular, cIAP2, Inhibitor of Apoptosis 2, API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, MIHC, TNFR2-TRAF Signaling Complex Protein)

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£728.00

SKU:: B2050-01L
Purity:: Purified by immunoaffinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein encompassing a sequence within the cemter region of human BIRC3. Species Sequence Homology: bovine, 84%
Format:: Supplied as a liquid in PBS, pH 7, 0.025% Proclin-300, 20% glycerol
Extra Details:: Apoptosis inhibitor 2 (API2) is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. API2 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. The names of API1 and API2 have been confusing. Suffice it to say that 'apoptosis inhibitor 2' is hiap-1 (inhibitor of apoptosis 1). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:3000 Immunohistochemistry (FFPE): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice