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B1078-75

Berninamycin A (Berninamycin, Antibiotic U27810)

Size

£576.00

SKU:
B1078-75
Molecular Weight:
1146.121
Purity:
>99%
Storage Conditions:
4°C/-20°C
Supplier:
United States Biological
CAS Number:
58798-97-3
Format:
White solid
Extra Details:
Berninamycin A is an antibiotic discovered in 1976 from a strain of Streptomyces. Berninamycin A is a macrocyclic "peptide" comprising atypical amino acids linked to thiazole and oxazoles. Chemically very complex, berninamycin A is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, members of the MerR proteins that are central regulators in multidrug resistence. Closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1. DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water
Shipping Conditions:
Blue Ice