B0807-52

BCMA (B Cell Maturation Protein)

Size

£723.00

SKU:: B0807-52
Purity:: Purified by Protein G affinity chromatography from concentrated tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Recombinant protein corresponding to aa1-46 from mouse BCMA at the extracellular domain.
Clone:: 6D163
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:: BCMA is a member of the TNF receptor superfamily. It binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines. It plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184aa type I transmembrane protein, which contains a 54aa extracellular domain, a 23aa transmembrane domain, and a 107aa extracellular domain. Applications: Suitable for use in Immunoprecipitation, Flow Cytometry, Western Blot and Functional Applications. Other applications not tested. Recommended Dilutions: Immunoprecipitation: 1:200 Flow Cytometry: 1:1000 Western Blot: 1:1000 Functional Application: Blocks binding of BAFF to mouse BCMA. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.