A4190-17H
Aurora C, ID (Aurora/IPL1/Eg2 Protein 2, Aurora/IPL1-related Kinase 3, Serine/Threonine Protein Kinase 13, Aurora-related Kinase 3, ARK-3, Aurora Kinase C, Serine/Threonine-protein Kinase Aurora-C, AURKC, AIE2, AIK3, ARK3, STK13)
Size
£696.00
- SKU:
- A4190-17H
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide selected from the center region of human Aurora-C (KLH).
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Extra Details:
- Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase. Applications: Suitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunofluorescence: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice