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A3690

Ascochlorin (Antibiotic LL-Z 1272 gamma)

Size

£473.00

SKU:
A3690
Molecular Weight:
404.9
Purity:
>95% by HPLC
Storage Conditions:
+4°C
Supplier:
United States Biological
CAS Number:
26166-39-2
Extra Details:
The antitumour fungal metabolite ascochlorin specifically inhibits matrix metalloproteinase-9 (MMP9) activity through suppression of activator protein-1 (AP-1) dependent induction of MMP-9 gene expression. Via AP-1 suppression ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Shipping Conditions:
Blue Ice