A2299-85
Apoptolidin
Size
£464.00
- SKU:
- A2299-85
- Molecular Weight:
- 1129.37
- Purity:
- >95% by HPLC
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 194874-06-1
- Extra Details:
- Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene at an IC50 = 11 ng/ml. It is among the most selective cytotoxic agents tested by the NCI in human cancer cell lines. Although the apoptotic activity of apoptolidin correlates with F0F1-ATPase inhibition, recent evidence suggests the existence of a secondary biological target or more complex mode of action. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO Related to: Isoapoptolidin
- Shipping Conditions:
- Blue Ice