A2299-75E

Apolipoprotein E (ApoE, AD2, MGC1571, Apoprotein, Apolipoprotein E, Apolipoprotein E3, Alzheimer Disease 2 (APOE*E4-associated, late onset))

Size

£642.00

SKU:: A2299-75E
Purity:: Purified by affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-VGTSAAPVPSDNH from the C-Terminus of human APOE.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought to be involved in tissue repair as increase amounts of the protein are found at sites or peripheral nerve injury and regeneration. A mutant form is associated with familial type hyperlipoproteinemia. Applications: Suitable for use in ELISA and Western Blot. Other Applications not tested. Recommended Dilutions: ELISA (Peptide): 1:128,000 Western Blot: 0.05-0.1ug/ml ~36kD band observed in human (Hippocampus) brain lysates Optimal dilutions to be determined by the researcher Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.