Apigenin (4',5,7-Trihydroxyflavone)

Size

£397.00

SKU:: A2298-78
Molecular Weight:: 270.24
Purity:: ≥97%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 520-36-5
Format:: Light yellow to dark yellow solid
Extra Details:: Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignan. Apigenin is a 270Da flavonoid, which belongs to the flavone group of glycosides. It is synthesized by a wide variety of plants including cereals, grains, tea and oranges. Apigenin has been used as a calibration standard for the quantification of Hieracium pannosum Boiss, Juniperus sp, using high-performance liquid chromatography (HPLC) with Diode-Array Detection (DAD). It has been used to study effect on hormone secretion in the human adrenocortical H295R cells. Synonyms: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxyflavone; Pelargidenon 1449 CAS No: 520-36-5 Molecular Formula: C₁₅H₁₀O₅ Molecular Weight: 270.24 Appearance: Light yellow to dark yellow solid Purity: ≥97% Melting Point: >300°C (lit.) Solubility: DMSO (Slightly), Methanol (Slightly, Heated) Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.