Anguinomycin A (5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A)

Size

£559.00

SKU:: A2295-11L1
Molecular Weight:: 512.68
Purity:: >95% by HPLC
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 111278-01-4
Extra Details:: Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumour activity in mice against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of Leptomycin B, an inhibitor of nuclear export of proteins. Purity: >95% by HPLC Solubility: Soluble in ethanol or methanol. Ethanol recommended. Unstable in DMSO. Related to: Leptomycin A, Leptomycin B, Kazusamycin A, Kazusamycin B