A2295-07T4
Angiotensin II Type 2 Receptor (AGTR2, AT2, MRX88) (PE)
Size
£741.00
- SKU:
- A2295-07T4
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- 4°C Do not freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- HEK293 human embryonic kidney cell line transfected with Met1-Ser363 of human Angiotensin II Type 2 Receptor.
- Clone:
- 8H158
- Format:
- Supplied as a liquid in PBS, 0.5 BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
- Extra Details:
- AGTR-2, also known as AT2, is a 7 transmembrane domain protein that belongs to the G protein-coupled receptor family 1. Both AGTR-2 and AGTR-1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR-1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 1x10e6 cells using NSO mouse myeloma cell line transfected with Angiotensin II Type 2 Receptor Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice