A2293-10
Angiopoietin 2 (Ang-2, AGPT2, ANGPT2, Ang2) (Not for Export EU)
Size
£672.00
- SKU:
- A2293-10
- Purity:
- Neat serum
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic 22aa amino acid peptide sequence near the N-terminal of mouse Ang-2 (KLH). . Species Sequence Homology: rat: 100%; porcine: 85%, human: 71%; chicken: 55%.
- Format:
- Supplied as a lyophilized powder, 0.05% sodium azide. Reconstitute with 100ul sterile PBS.
- Extra Details:
- Angiopoietin-1 is an angiogenic secreted protein that interacts with endothelial specific Tie-2 receptor. It is primarily expressed in developing endothelial cells. During embryonic development, Ang-1 binds and induces tyrosine phosphorylation of Tie-2. Ang-1 may play a critical role in heart development. A homolog of Ang-1, termed Angiopoietin-2 (mouse and human Ang-2, 496 AA; ~85% identity) has recently been identified. It may act as an antagonist for Ang-1 and Tie-2. Ang-1 and Ang-2 have ~60% sequence homology. It is prominently expressed in tissues that are in involved in vascular remodeling (ovary, placenta, and uterus). Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:10,000-1:100,000 (50-100ng of control peptide/well) Optimal dilutions to be determined by the researcher. Control Peptide (ELISA): A2293-12 Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice