A2275-75N
Amyloid Beta, 1-42 (CT) (Amyloid A4)
Size
£787.00
- SKU:
- A2275-75N
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to the last 6aa of human ABx-42 conjugated to KLH through the addition of an N-terminal cysteine.
- Clone:
- 9L34 (12F4)
- Format:
- Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride. 0.05% sodium azide.
- Extra Details:
- Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Ab4) protein has been found to be the principal constituent of senile plaques of ADs patients. The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD Ab4 protein. Two variants of Ab4 can be detected; Ab-40 short-tailed and Ab-42 long-tailed. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:100-1:1000 Immunohistochemistry (FFPE): 1:100-1:2000. Pretreat sections with 70% formic acid for 10-30 minutes. Antibody should be incubated with sections overnight at 4ºC. Optimal dilutions to be determined by the researcher. Positive Control: Human Alzheimer's brain tissue. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice