A1061
AHSP, Recombinant Human (Alpha-hemoglobin-stabilizing protein, EDRF, ERAF, Erythroid associated factor, Erythroid differentiation-related factor)
Size
£497.00
- SKU:
- A1061
- Molecular Weight:
- 11.8
- Purity:
- ~95% (SDS-PAGE) Purified by immunoaffinity chromatography.
- Storage Conditions:
- -70°C
- Supplier:
- United States Biological
- Format:
- Supplied as liquid in 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol.
- Extra Details:
- AHSP (Alpha-hemoglobin stabilizing protein), also known as ERAF (Erythroid associated factor), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of aplha-hemoglobin during normal erythroid cell development. It specifically protects free alpha-hemoglobin from precipitation in live cells and in solution. This protein is downregulated in transmissible spongiform encephalopathies (TSEs). It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. Recombinant AHSP protein, expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding to human AHSP, 1aa-102, expressed in E. coli. AA Sequence: MALLKANKDL ISAGLKEFSV LLNQQVFNDP LVSEEDMVTV VEDWMNFYIN YYRQQVTGEP QERDKALQEL RQELNTLANP FLAKYRDFLK SHELPSHPPP SS Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
- Shipping Conditions:
- Dry Ice