A1059-53W
Aggrecan, NT (Proteoglycan, PG, AGC 1, Aggrecan 1, Antigen Identified by Monoclonal A0122, Cartilage Specific Proteoglycan Core Protein, Chondroitin Sulfate Proteoglycan Core Protein 1, CSPCP, CSPG1, CSPGCP, Large Aggregating Proteoglycan, MSK16, SEDK)
Size
£806.00
- SKU:
- A1059-53W
- Application:
- IP
- Purity:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to Leu384-Glu392 from human Aggrecan, conjugated to KLH.
- Clone:
- 11n4
- Format:
- Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- Aggrecan, together with type II collagen, makes up to 90% of the dry weight of healthy cartilage. It hydrates the collagen network and thus provides cartilage with its properties of compressibility and elasticity. The N-terminal region of human Aggrecan (residues 20-675) consists of two globular domains (G1 and G2), flanking an interglobular domain (IGD). The IGD contains the cleavage sites for matrix metalloproteinases and aggrecanases. Applications: Suitable for use in Immunoprecipitation. Other applications not tested. Recommended Dilution: Immunoprecipitation: 25ug/ml with conditioned cell culture medium spiked with ADAMTS5 cleaved recombinant human aggrecan Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder and reconstituted products must be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Reconstitute with sterile PBS. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice