A0925-01-BIOTIN
Aflatoxin B, pan (Biotin)
Size
£916.00
- SKU:
- A0925-01-BIOTIN
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Aflatoxin of Aspergillus flavus origin
- Clone:
- 2F10
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
- Extra Details:
- Aflatoxin is a potent carcinogen. The fungus, genus Aspergillus, that secretes aflatoxin enters the plant usually through the wounds left by an insect pest, since most plants have a hard outer layer that acts as a barrier to fungi. Once inside the plant, the fungus can reach all parts of the plant, including its seeds. Aflatoxin is a serious cause of illness and death in developing countries which have fewer food safety regulations. Some plant scientists are trying to develop transgenic corn with a gene for an enzyme which breaks down aflatoxin. Aflatoxin is listed as a possible carcinogen, and has been shown to cause liver damage, some of which may be cumulative, in many mammals that ingest sufficient quantities of it, though tolerance seems to vary by species. In most species, aflatoxin cannot be detected in the liver 14 days after it has been withdrawn from the animals diet, though some of its effects may still be present. Animals affected by aflatoxicosis show reduced feed intake, and even mortality, if sufficient amounts of aflatoxin are ingested for a sufficient period of time. Sensitivity, however, seems to vary not only by species, but also by individual animals. Affinity Constant: ~6.6x10e9L/M Applications: Suitable for use in ELISA and Binding assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice