A0859-20E

ADAM10 (Kuzbanian, KUZ, MADM, A Disintegrin and Metalloprotease 10) (Carboxyfluorescein)

Size

£639.00

SKU:: A0859-20E
Application:: Flow Cytometry
Purity:: Purified by Protein A affinity chromatography from hybridoma culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to Thr214-Glu672 from human ADAM10, expressed in NSO cells.
Clone:: 9H29
Format:: Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Carboxyfluorescein.
Extra Details:: ADAM10 is a transmembrane multiple domain protein with ubiquitous expression. The metalloprotease activity of ADAM10 can cleave several molecules including Notch, pro-TNF- alpha, amyloid precursor protein, myelin basic protein, and type IV collagen. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels 1x10e6 cells in MCF‑7 human cell line Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Carboxyfluorescein conjugates are sensitive to light.