A0758-07

ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

Size

£294.00

SKU:: A0758-07
Purity:: Purified by Protein A affinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Clone:: 1.B.55
Format:: Supplied as a liquid in PBS, pH 7.6, 0.09% sodium azide
Extra Details:: Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease Applications: Suitable for use in Immunohistochemistry, ELISA and other solid-phase assays. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Formalin-fixed, paraffin-embedded tissue Optimal dilutions to be determined by the researcher. Affinity Constant: >10e11 L/mole Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.