A0001-98

AASS, ID (Alpha-aminoadipic Semialdehyde Synthase, Mitochondrial, LKR/SDH, Lysine Ketoglutarate Reductase, LKR, LOR, Saccharopine Dehydrogenase)

Size

£696.00

SKU:: A0001-98
Purity:: Purified by ammonium sulfate precipitation
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to a portion of amino acids within aa272-301 from the center region of human AASS. conjugated to KLH.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:1000 Western Blot: 1:50-1:100 Immunohistochemistry (Paraffn): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.