A0001-85

17-AAG (17-allylamino-17-demethoxygeldanamycin, Telatinib, Tanespimycin, NSC-330507, CNF-101, KOS-953, GLD-36, CP 127374)

Size

£375.00

SKU:: A0001-85
Molecular Weight:: 585.69
Purity:: ~99%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 75747-14-7
Format:: Supplied as a purple powder.
Extra Details:: Semi-synthetic derivative of geldanamycin, demonstrating greater stability and lower in vivo toxicity than its parent compound. 17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Solubility: Soluble in DMSO at 150mg/ml; soluble in ethanol at 5mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 20-50uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Melting Point: As Reported Elemental Analysis: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. .