591990

CD47, Magrolimab Biosimilar

Size

£576.00

SKU:: 591990
Purity:: Purified by Protein A/G affinity chromatography. Endotoxin: ≤1EU/mg (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Human
Immunogen:: Recombinant protein corresponding to humanized CD47, expressed in CHO cells.
Format:: Supplied as a liquid in PBS. No preservative added.
Extra Details:: Magrolimab is anti-CD47 monoclonal antibody designed to promote phagocytosis of cancer cells by macrophages. Its purpose is to interfere with the recognition of CD47 by SIRPalpha receptors on macrophages, thereby blocking the self-protection signals used by cancer cells to avoid being swallowed by macrophages. Applications: Suitable for use in Functional Assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Extinction Coefficient: 1.607 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.